Yup, totally doable.
Ive used:
* Pinnacle Dazzle capture: http://www.bhphotovideo.com/bnh/controller/home?O=&sku=1015438&gclid=CKmDlueQoscCFc4XHwodeL4EbQ&is=REG&m=Y&A=details&Q=
* Video Glide compatible drivers: https://www.echofx.com/videoglide.html
* High quality pro capture gear from Aja and BlackMagic
And other solutions. All work, all can be seen by compatible syphon software like VDMX, Jitter, QC, Max, Resolume etc.
Totally doable 🙂